Character Biosciences

About the Company

Character Biosciences is a precision medicine company transforming drug development for progressive, polygenic diseases, beginning with ophthalmology. Our mission is to identify the genetic and molecular drivers of disease progression so we can develop targeted therapies for patients who urgently need them. We've built one of the most comprehensive resources in age-related eye diseases by partnering with over 150 ophthalmology clinics to integrate genetics with longitudinal clinical and imaging data. This deep phenotyping approach enables us to reclassify complex diseases like age-related macular degeneration (AMD) into genetically defined subtypes, unlocking novel therapeutic targets and optimizing patient selection for clinical trials. Character Bio's AI-powered platform combines genomics, multi-modal data, and machine learning to discover and develop therapies that are more precise and more effective. Our lead programs, CTX114 and CTX203, are advancing toward clinical trials and are designed to slow or prevent vision loss in AMD patients. We are committed to delivering a new generation of precision medicines to treat and ultimately cure age-related blindness.

Listed Jobs

Company Name

Character Biosciences

Job Title

Principal Biostatistics Data Scientist

Job Description

**Job Title** Principal Biostatistics Data Scientist **Role Summary** Lead the design, execution, and operationalization of advanced biostatistical and data science analyses that drive drug discovery, clinical trial planning, and biomarker development in precision medicine. Provide statistical leadership, mentorship, and cross‑functional collaboration to translate complex multimodal data into actionable insights. **Expectations** - Immediate engagement as a contractor with potential transition to full‑time. - Deliver rapid, high‑impact analytical solutions in a lean, fast‑moving environment. - Communicate findings clearly to scientific, clinical, and executive stakeholders. - Contribute to strategic data science roadmap and scientific publications. **Key Responsibilities** - Design and implement survival, mixed‑effects, Bayesian, and machine‑learning models for quantitative biomarker discovery, disease progression prediction, and clinical trial design. - Develop and validate longitudinal models using EMR, genomics, and ophthalmic imaging data. - Mentor and guide data science team members on statistical best practices and analytical methods. - Collaborate with genomics, clinical research, and biology teams on integrated, cross‑functional projects. - Contribute to strategic planning, data architecture, and analytics road‑mapping. - Prepare scientific manuscripts and presentations communicating data science findings. **Required Skills** - 7+ years in applied biostatistics or data science within life science/healthcare. - Deep expertise in survival analysis, mixed‑effects modeling, Bayesian inference, and advanced machine‑learning techniques. - Proficiency in Python or R and modern data science frameworks. - Experience with real‑world longitudinal biomedical data (EMR, genomics, imaging). - Strong problem‑solving, data‑driven decision making, and cross‑functional communication. **Required Education & Certifications** - PhD in Biostatistics, Data Science, Computer Science, or a closely related field. ---

Brisbane, United states

Hybrid

Senior

26-09-2025