cover image
Pebble Biotechnology Laboratories

Pebble Biotechnology Laboratories

pebble.bio

1 Job

15 Employees

About the Company

Our next-generation LIVING-ORGAN systems support researchers in developing tangible healthcare products and innovations. Line-of-sight to patients is important to us and sits closely with our strong moral objective to improve patients lives. We progress an asset from a pipeline hypothesis through to clinical trial via three packages: Package 1 - FAST-TO-POC: Quick to fail/proceed analysis of a pre-pipeline asset with a focus on safety. De-risking investments and increasing confidence that an asset will proceed to an MHRA/EMA/FDA submission Package 2 - INTERNAL R&D in Stealth: Rapid generation of non reportable data of an asset - Detailed safety, immune profiling, organ-specific toxicities, evaluation of efficacy, on/off target effects. Enables commercially safe fail-iterate-repeat experiments Package 3 - MHRA/EMA/IND READY DATA: Preclinical Pharmacology and Toxicology Studies – to confirm an asset is reasonably safe for initial testing in humans. We are FASTER – We are a non-bureaucratic organisation. Our models do not need regulatory approval, meaning time-to-start is in days rather than months, resulting in high intensity data generation. We are responsive to data, allowing study designs to pivot and enabling highly iterative R&D. We are BETTER – We are a team of world leading experts with a collective experience in decades. Our technology is the most advanced in the world, only using state-of-the-art critical care equipment and MHRA/EMA/FDA approved tech. We are CHEAPER – On average we result in a 90% cost-saving compared to NHP in-vivo experiments. We act as your external ‘white-label’ R&D partner, significantly reducing your infrastructure costs and enabling a fee-per-project service. We are SECURE – We do not claim any IP related to your innovations. We serve a global market, with partners in the UK, Europe and America. Our team of data analysts and senior scientists provide a complete data package for 'stealth' R&D or clinical trial submission

Listed Jobs

Company background Company brand
Company Name
Pebble Biotechnology Laboratories
Job Title
Industrial Placement Student
Job Description
**Job Title** Industrial Placement Student **Role Summary** Provide day‑to‑day laboratory support for normothermic machine perfusion (NMP) experiments, including solution preparation, perfusion circuit assembly, blood cell saving, sample processing, data recording, and laboratory maintenance. Work on a rotating schedule that includes day and night shifts, and participate in experimental design discussions and protocol development. **Expectations** - Participate in a structured induction and ongoing training program. - Work full time on a rota (days and nights) while maintaining laboratory standards and safety. - Act as a core member of the team, collaborate with academic and clinical experts, and contribute to meetings, presentations, and project updates. - Receive regular mentoring from a Senior Scientist and scheduled one‑to‑one progress reviews. **Key Responsibilities** - Weigh, mix, and pH‑balance perfusion solutions. - Assemble and set up normothermic perfusion circuits, including blood‑cell‑saver machines. - Prepare and draw therapeutics required for each experiment. - Conduct blood‑cell‑saving procedures on experiment days. - Operate NMP systems, monitor physiological parameters, perform arterial blood gas analysis, collect samples, and manage post‑experiment clean‑down. - Label, process, aliquot, freeze (liquid nitrogen, OCT), and store samples with traceability. - Record all data accurately in paper and electronic forms. - Maintain stock levels, order supplies, and coordinate with stock control. - Organise and store chemicals, fluids, and gases following safety protocols. - Review relevant literature to support protocol discussions and experimental planning. - Attend laboratory and monthly presentation meetings, contributing updates and insights. - Perform general laboratory upkeep, ensure a clean environment, and enforce safety guidelines. **Required Skills** - Laboratory technique: pipetting, centrifugation, basic dissection, suturing, liquid nitrogen handling. - Knowledge of porcine anatomy and basic surgical procedures. - Ability to prepare and handle perfusion solutions and therapeutics. - Data entry, record‑keeping, and laboratory documentation. - Strong teamwork, communication, and problem‑solving skills. - Adherence to safety procedures and laboratory protocols. **Required Education & Certifications** - Current enrolment in or completion of a degree in Biomedical Sciences, Physiology, Biotechnology, or related field. - No specific professional certification required; willingness to complete on‑the‑job training in NMP and related skills.
Styal, United kingdom
On site
04-11-2025