Skills

Communication Test Problem-solving Technical Writing Attention to detail Organizational Skills

Job Specifications

Analytical Chemist

Boston, MA

Schedule: Hybrid - 3 days onsite

Duration: 12-Month Contract (opportunity to extend)

Pay: $66-71/hr (W2)

Our client is a leading biotechnology company specializing in advanced therapeutics. They are seeking an experienced Analytical Chemist to join their growing Technical Operations Analytical team. This hybrid role has the primary responsibility to provide analytical support for Oligonucleotides and Peptides in late-stage phase, with opportunities to lead method development and validation activities independently.

Essential Functions and Responsibilities

Provide analytical support for Oligonucleotide and Peptide-Oligonucleotide conjugated compounds
Develop and optimize robust LC/MS, IPRP, and SAX HPLC analytical methods for analysis and purification of highly modified oligonucleotide drug substances
Utilize IP-RP-HPLC, AX-HPLC, UPLC, LC-MS, and LC-MS/MS analytical techniques using Agilent, Waters, and/or Thermo instruments and associated software
Operate, maintain, and troubleshoot laboratory instruments
Perform method validation and transfer activities in compliance with GLP/GMP standards
Collect, document, and analyze test data with strict attention to detail
Draft technical reports, analytical methods, and validation documentation
Collaborate with cross-functional teams across Technical Operations
Train and mentor team members on analytical procedures and instrumentation
Support late-stage phase analytical activities for oligonucleotide therapeutics

Education and Experience

MS or BS in Chemistry, Analytical Chemistry, or related field
3+ years of industrial experience in pharmaceutical or biotechnology environment
Strong background in analytical development and validation of methods for analysis of oligonucleotide therapeutics required
Experience with late-stage phase analytical support preferred

Knowledge and Skills

Strong background in analytical development and validation of oligonucleotide therapeutics
Strong knowledge of mass spectrometry and purification techniques
Expertise with IP-RP-HPLC, AX-HPLC, SAX-HPLC, UPLC, LC-MS, and LC-MS/MS analytical techniques
Experience with Agilent, Waters, and/or Thermo instrumentation and associated software
In-depth knowledge of GLP/GMP requirements in a pharmaceutical environment
Knowledge of cGMP practices and documentation requirements
Strong problem-solving methodology and root cause analysis skills
Excellent technical writing and communication skills
Demonstrated ability to work independently and with cross-functional teams
Committed team player and collaborator
Ability to operate, maintain, and troubleshoot complex laboratory instruments
Strong attention to detail and organizational skills
Computer skills including MS Office Suite and chromatography data systems
Ability to develop and optimize robust analytical methods
Knowledge of validation and method transfer processes

About the Company

At Hydrogen Group, we enable people to live healthier, happier, more fulfilling and more successful lives in a rapidly changing world. We do this every day by giving people the tools they need to thrive. We know what works for one person, or business, won’t suit another, but if we can truly understand what type of people will thrive in your business, or what you need to Thrive in your own role, we’ll help you find that person or organisation to help you do just that. Our purpose will ensure that the people we work with ar... Know more