Skills

Communication Leadership Python Data Analysis Attention to detail Training Motivation

Job Specifications

Computational Scientist (Pathology)

$75 - $78/hr with medical benefits available at a cost

1 year initial contract with possibility of extension

Hybrid or remote out of South San Francisco

Orion Group and our largest US client are teaming up this holiday season for an exciting contract opportunity for a Computational Scientist!!! Our client is seeking candidates with a background in Computational Biology and advanced knowledge and experience analyzing spatial transcriptomics and proteomics data generated on the CosMx SMI and PhenoCycler Fusion platforms.

Apply today and head into the new year as a part of a market leading pharmaceutical company!!!

Purpose:

The Precision Medicine Pathology team drives the scientific strategy for translational tissue-based biomarker development & discovery target validation/MOA projects, leads pathology collaborative programs, conducts histopathological evaluation & analysis of IHC & spatial biology technologies, and provides technical/scientific leadership to histotechnicians & pathology scientists.

The successful candidate will have advanced knowledge and experience analyzing spatial transcriptomics and proteomics data generated on the CosMx SMI and PhenoCycler Fusion platforms.

Responsibilities:

Implementation of different scripts and pipelines for spatial transcriptomics data analysis and analysis of high-plex PhenoCycler Fusion (CODEX) images.
Independently performing end-to-end high-plex image analysis (tissue classification, cell segmentation, detection of marker positivity, cell phenotyping, unsupervised clustering, neighborhood analysis, proximity analysis).
Acting as a subject matter resource and training other team members in spatial analysis tasks.
Collaborating with pathologists and digital pathology scientists to support spatial biology projects.
Presenting the results and findings from spatial biology studies to stakeholders.

Qualifications needed:

MSc, PhD, or equivalent degree in biological sciences / computational biology / engineering / computer science / informatics
Fluency in Python and R is a must have
Experience analyzing spatial transcriptomics and proteomics data generated on the CosMx is a must have
Experience in implementing and utilizing open-source scripts and pipelines for high-plex image analysis
Experience in quantitative digital pathology analysis platforms such as Halo, Visiopharm, QuPath
Close familiarity with tissue microscopic anatomy and histology (normal and diseased) is a plus
Excellent verbal communication skills are required including the demonstrated ability to effectively and clearly summarize results for presentation and report generation
Strong motivation, attention to detail, ability to think independently and fully integrate into a high achieving team environment
Ability to multi-task and manage multiple projects

Our role in supporting diversity and inclusion

As an international workforce business, we are committed to sourcing personnel that reflects the diversity and values of our client base but also that of Orion Group. We welcome the wide range of experiences and viewpoints that potential workers bring to our business and our clients, including those based on nationality, gender, culture, educational and professional backgrounds, race, ethnicity, sexual orientation, gender identity and expression, disability, and age differences, job classification and religion. In our inclusive workplace, regardless of your employment status as staff or contract, everyone is assured the right of equitable, fair and respectful treatment.

About the Company

Established in Scotland in 1987, Orion Group achieved consistent growth over the ensuing 38 years and is now an international leader in the provision of personnel. We manage thousands of contractors and permanent placements from our worldwide network of offices throughout the Americas, the UK and Europe, the Middle East and Asia Pacific regions. Know more