Bioinformatician

Skills

Job Specifications

About Healx
Healx is an AI-powered tech bio company that is redesigning drug discovery. With 10,000 rare diseases affecting 400 million people globally, 90% of which have no approved treatment, Healx is on a mission to pioneer the next generation of drug discovery to help rare disease patients in need. We combine data, artificial intelligence and deep pharmacology expertise to develop treatments more quickly and cheaply than traditional drug discovery.

Diversity and inclusion sits at the heart of our mission to help people with rare diseases, and we believe that attracting and empowering a diverse team is critical to achieving this goal. We welcome applications from people from all backgrounds and walks of life.

Below we have included the qualities that we feel are required for you to excel in this role; however we appreciate that people can apply transferable skills from all walks of life and experience. If you think you have what it takes, love our mission and resonate with our values but are worried you don't tick every box – we still want to hear from you and encourage you to apply!

Our values

Care for Rare – Rare disease patients are at the heart of what we do
Grow as individuals – We are learners always seeking to enhance our expertise
Win as a team – We strive to remain inclusive and diverse and we celebrate successes and lessons together
Innovate and deliver – Our mission requires rapid innovation and calculated risks that won’t compromise our high standards

The role

Healx is looking for an enthusiastic Bioinformatician to join the Digital Sciences team to play a key role in Bioinformatic activities that improve outcomes for rare disease patients by discovering drug combination therapies with improved efficacy and safety over standard of care. This role will enhance the capabilities of our AI Drug Discovery Platform. You will support development of novel algorithms for the prediction of drug synergy and polypharmacology required by our growing portfolio of Rare Neurology and Oncology Programmes. You will partner closely with and report to the Senior Director of Digital Science to plan, develop and deliver algorithms and bioinformatic workflows that generate therapeutic hypotheses. You’ll be closely collaborating with Pharmacologists, Biocurators, Data Engineers, Bioinformaticians, Cheminformaticians and Machine Learning Engineers & Scientists to deliver in silico predictions that will be experimentally tested. Owing to the unique cross functional and highly collaborative Healx Team, the research you perform will be rapidly translated to meaningful outcomes, with the potential to improve patient quality of life.

Key Responsibilities

Application of drug combination prediction algorithms to generate and rationalise novel therapeutic hypotheses for Healx portfolio of rare diseases
Innovation and improvement of Healx drug combination technologies
Supporting the Healx Preclinical Team to deliver the best outcomes for rare disease patients by ensuring our AI Discovery Platform is maintained

You will know you are successful when

Digital Science delivers the best treatment predictions with highest chance of clinical and commercial success to our Pharmacologists
Algorithm and workflow improvements you’ve contributed are applied in active Preclinical Discovery Programmes
You are actively developing high quality code in collaboration with colleagues, and receiving great feedback on your commits

What We're Looking For

You have experience in Biotech or Pharma Bioinformatics, a background in human disease biology, and you’re now looking for your next challenge. You are excited about taking on new projects and responsibilities in a mission-driven startup. We'd love to hear from you if your experience and interest overlaps with this profile:
Bioinformatics, especially processing multiomics, compound bioactivities or other life sciences data for the discovery of drug combinations
Reduction of algorithms to code, especially in Python, R, and Nextflow Pipelines
Hands-on and collaborative approach to Bioinformatic algorithm and workflow development
Interest in biotech/ techbio and its impact of improving patient outcomes
It’s a bonus if you have:
Experience estimating synergy, polypharmacology or adverse events
Familiarity with network biology methods, elucidation of signalling pathways and gene set enrichment
A keen interest in Bioinformatic Engineering standards
A background in health-tech or life sciences

Working at Healx

Healx works from a modern accessible office in the centre of Cambridge within easy reach of the train station. We offer a flexible, diverse and inclusive working environment that considers your individual needs and believes in maintaining a sustainable work-life balance and we are open to discussing flexible working arrangements. You will be welcomed by a team of colleagues with decades of accumulated experience in their areas of expertise, happy to help you develop your own skills in

About the Company

Healx is a mission-driven technology company pioneering the next generation of drug discovery in order to bring novel, effective treatments to rare disease patients around the world. There are more than 10,000 known rare diseases that affect 400 million people across the globe, but only 5% of those conditions have an approved treatment. By combining frontier AI technology with deep drug discovery and development expertise, Healx can accelerate the pace, increase the scale and improve the chance of success of rare disease tre... Know more

Related Jobs

Company Name

Isomorphic Labs

Job Title

Senior Machine Learning Engineer

London, United kingdom

On site

Full Time

13-03-2026

Company Name

Owen Thomas

Job Title

Director of AI/Machine Learning, Drug Discovery | Pharma/BioTech | Series A - B2B Platform | EU Remote | | Salary Up to £200,000, plus early equity+benefits

England, United kingdom

On site

Full Time

20-02-2026

Company Name

Owen Thomas

Job Title

Director of Computational Drug Discovery, AI/Machine Learning | Pharma/BioTech | Series A - B2B Platform | EU Remote | | Salary Up to £200,000, plus early equity+benefits

England, United kingdom

On site

Full Time

06-02-2026