Skills

Leadership Research

Job Specifications

Mantell Associates is partnered with a fast-growing AI-centric biotech organisation, who is searching for a highly motivated and experienced Clinical Pharmacologist to lead translational science initiatives and drive quantitative decision‑making across our preclinical and early clinical programs.

Clinical Pharmacologist - Responsibilities:

Lead clinical pharmacology strategy for AI‑driven small molecule and biologic programs, including dose prediction, modelling, simulation, and translational biomarkers
Design and interpret PK/PD studies to inform candidate selection and optimisation across discovery and early development
Collaborate with cross‑functional teams (AI/ML scientists, medicinal chemists, toxicologists, clinicians) to integrate clinical pharmacology insights into project decisions
Develop innovative approaches to leverage AI platforms for predictive pharmacology and optimise clinical trial design
Provide scientific leadership on regulatory submissions and interactions related to pharmacokinetics, pharmacodynamics and dosing rationale
Apply quantitative systems pharmacology (QSP) and population modelling to support patient stratification and dose selection
Mentor and guide junior scientific staff within the translational science function

Clinical Pharmacologist - Requirements:

Advanced degree (PhD, PharmD or equivalent) in Clinical Pharmacology, Pharmacokinetics, Pharmacology or related discipline
Demonstrated expertise in clinical pharmacology within biotech, pharma, or translational research
Strong experience in PK/PD modelling, physiologically‑based pharmacokinetics (PBPK), population PK, and quantitative analysis
Familiarity with AI/ML applications to drug discovery or clinical trial data is highly desirable
Excellent communicator with ability to articulate complex scientific concepts to multidisciplinary audiences
Proven track record of delivering translational outcomes that advance drug candidates toward clinical success
Based in the UK (or eligible to work in the UK), with flexibility for occasional travel

Mantell Associates is a specialist Pharmaceutical and Life Science headhunting firm. For more information on this opportunity, contact us at +44 (0)20 2854 7700.

About the Company

Mantell Associates is a multi-discipline headhunting firm focused on providing both permanent and contract recruitment services globally, to the Biotech, Pharmaceutical, CDMO, CRO, Diagnostics, Animal Health, Consulting, Medical Device and MedTech sectors. With success ranging across C-Suite, Commercial, Technical Operations, Scientific, Clinical, Quality and Regulatory, we pride ourselves on our ability to bring the top talent to our clients, and the best opportunities to the top talent. Our services span across our Pa... Know more