Job Specifications
Location of role Oxford, UK
Department Biology Pipeline
Key Responsibilities Purpose of the role
We are seeking a motivated student to join our Nonclinical Safety Team to work on engineering cell models to evaluate novel bispecific molecules. You will use state‑of‑the‑art genetic engineering tools to perturb specific genes or introduce synthetic molecular circuits into mammalian cells (e.g. knock‑out, upregulation, gene modulation) and generate robust in vitro models for pharmacological testing.
This role offers hands‑on training in advanced molecular biology and cell biology techniques directly applied the discovery and assessment of novel Immuno-engagers.
Key Responsibilities
(Training and guidance will be provided)
Genetic Engineering and Cell Line Development
In silico design of synthetic nucleic acid sequences (e.g., sgRNAs, plasmids)
Generation and propagation of plasmid stocks, molecular cloning.
Generate, characterize, and maintain engineered cell lines for use in preclinical assays
Validate genetic perturbations at the DNA, RNA, and/or protein level (e.g., PCR/qPCR, western blot, flow cytometry, immunofluorescence, Next Generation Sequencing).
Apply engineered cell models to assess the pharmacological effects of bispecific molecules.
Perform cell based assays (e.g. co-culture with immune cells, T cell activation assays, killing assays, cytokine release assays) to study pharmacological responses to gene perturbation.
Assist with the isolation of specific cell population using Fluorescence Assisted Cell Sorting (FACS).
Data Analysis and Documentation
Analyze data, generate summary reports, interpret results.
Maintain detailed electronic laboratory notebooks, protocols, and records in accordance with company’s policies and industry standards.
Present results in internal meetings and contribute to internal reports or presentations.
Laboratory Operations
Perform routine laboratory maintenance tasks.
Follow all safety, biosafety, and quality guidelines.
Education And Qualifications
Candidates need to be undertaking (currently in second year and looking for a year in industry) a BSc. in Biological or Biomedical Sciences, Biochemistry, Immunology, Pharmacy, Pharmacology, or related disciplines.
What will you receive?
Join Immunocore for a paid placement and gain insights from our innovative science and corporate growth. You’ll enjoy 25 days of annual leave (pro rata), pension scheme eligibility, and access to our active Sports and Social Club with subsidized events.
Please note this is a full-time position is based at our Abingdon, Oxfordshire office and contracted through a third party.
Important information for all applicants
The application deadline is 09th January 2026, with phone interviews starting shortly after. Shortlisted candidates will be invited to an in-person Assessment Centre on 23rd, 24th, 25th, or 26th February 2026, providing an opportunity to meet current placement students, learn about the role, and socialize with employees.
Placements are expected to begin on 7th September 2026.
Please note - should you not be available on all the above dates, unfortunately, we won't be able to proceed with your application.
If interested, apply with your CV and a cover letter (combined in one document) stating your main areas of interest.
About the Company Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry’s most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.
Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases.
At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients’ lives, advancing medicine, and supporting one another in these pursuits.
Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, an